Estimated delivery in United States, on Tuesday 10 Dec 2024
Product Information
Name:
Alectinib M4 metabolite-d4
Controlled Product
Synonyms:
- 9-Ethyl-6,11-dihydro-8-[4-[(2-hydroxyethyl)amino]-1-piperidinyl]-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile-d4
Description:
Applications Alectinib M4 metabolite-d4 is the labelled analogue of Alectinib M4 metabolite (A521152) which is a major active metabolite of Alectinib. Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor and is used to treat non-small-cell lung cancer by blocking the activity of anaplastic lymphoma kinase (ALK).
References Heinig, K., et al.: Bioanalysis, 8, 1465-79 (2016); Morcos, P.N., et al.: Xenobiotica, 47, 217-29 (2017);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
460.604
Formula:
C28D4H28N4O2
Color/Form:
Neat
InChI:
InChI=1S/C28H32N4O2/c1-4-18-14-21-22(15-24(18)32-10-7-19(8-11-32)30-9-12-33)28(2,3)25-20-6-5-17(16-29)13-23(20)31-26(25)27(21)34/h5-6,13-15,19,30-31,33H,4,7-12H2,1-3H3/i9D2,12D2
SMILES:
[2H]C([2H])(O)C([2H])([2H])NC1CCN(c2cc3c(cc2CC)C(=O)c2[nH]c4cc(C#N)ccc4c2C3(C)C)CC1
MDL:
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Technical inquiry about: TR-A521152 Alectinib M4 metabolite-d4
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