Aliskiren Hydrochloride

CAS: 173399-03-6

Ref. TR-A536000

Product Information

• Name: Aliskiren Hydrochloride
• Synonyms: Aliskiren hydrochloride,(alphaS,deltaS,gammaS,zetaS)-delta-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-gamma-hydroxy-4-methoxy-3-(3-methoxypropoxy)-alpha,zeta-bis(1-methylethyl)benzeneoctanamide Hydrochloride (1:1), Benzeneoctanamide, delta-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-gamma-hydroxy-4-methoxy-3-(3-methoxypropoxy)-alpha,zeta-bis(1-methylethyl)-, monohydrochloride, (alphaS,gammaS,deltaS,zetaS)- (9CI), Benzeneoctanamide, delta-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-gamma-hydroxy-4-methoxy-3-(3-methoxypropoxy)-alpha,zeta-bis(1-methylethyl)-, monohydrochloride, [alphaS-(alphaR*,gammaR*,deltaR*,zetaR*)]-
• Brand: TRC
• Description: Stability HygroscopicApplications An orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.References Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000), Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002), Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003), Grandman, A.H., et al.: Circulation, 111, 1012 (2005),

Chemical properties

• Molecular weight: 588.22
• Formula: C₃₀H₅₃N₃O₆·ClH
• Color/Form: Neat
• InChI: InChI=1S/C30H53N3O6.ClH/c1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36;/h10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35);1H/t22-,23-,24-,25-;/m0./s1
• InChI key: InChIKey=BSJUIBZAXCXFMZ-NATPOTRJSA-N
• SMILES: COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@H](C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC.Cl