Product Information
Name:(3a)-Allopregnanolone
Controlled Product
Synonyms:
- (+)-3alpha,-Hydroxy-5alpha,-pregnan-20-one
- (3alpha,,5alpha,)-3-Hydroxypregnan-20-one
- 3alpha,,5alpha,-THP
- 3alpha,,5alpha,-Tetrahydroprogesterone
- 3alpha,-Hydroxy-5alpha,-dihydroprogesterone
- 3alpha,-Hydroxy-5alpha,-pregnan-20-one
- 3alpha,-Hydroxy-5alpha,-pregnane-20-one
- 5alpha,-Pregnan-3alpha,-ol-20-one
- 5alpha,-Pregnane-3alpha,-ol-20-one
- Allopregnan-3alpha,-ol-20-one
- Allopregnanolone
- See more synonyms
Brand:TRC
Description:Applications (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain. In 2019, the US Food and Drug Administration approved (3α)-Allopregnanolone as an intravenous infusion for treating postpartum depression.References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:318.49
Formula:C21H34O2
Color/Form:White To Off-White
InChI:InChI=1S/C20H32O2/c1-19-9-7-15(22)11-13(19)3-5-16-17-6-4-14(12-21)20(17,2)10-8-18(16)19/h12-18,22H,3-11H2,1-2H3/t13-,14+,15+,16-,17-,18-,19-,20+/m0/s1
InChI key:InChIKey=AURFZBICLPNKBZ-SYBPFIFISA-N
SMILES:CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
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