Product Information
Name:17-(Allylamino-d5) Geldanamycin
Controlled Product
Synonyms:
- 17-Demethoxy-17-(2-propenylamino-d5)geldanamycin
- 17-(Allylamino-d5)-17-demethoxygeldanamycin
- 17-(Allylamino-d5)-17-desmethylgeldanamycin
- 17-Demethoxy-17-(allylamino-d5)geldanamycin
- 17AAG-d5
- CP 127374-d5
- KOS 953-d5
- NSC 330507-d5
- Tanespimycin-d5
Brand:TRC
Description:
Applications Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
References Schnur, R.C., et al.: J. Med. Chem., 38, 3806 (1995), Nimmanapalli, R., et al.: Cancer Res., 61, 1799 (2001), Basso, A.D., et al.: Oncogene, 21, 1159 (2002),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:590.719
Formula:C31D5H38N3O8
Color/Form:Neat
InChI:InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9-,18-10+,20-15+/t17-,19+,24+,25+,27-,29+/m1/s1/i1D2,8D,12D2
InChI key:InChIKey=AYUNIORJHRXIBJ-RDXCHMSBSA-N
SMILES:[2H]C([2H])=C([2H])C([2H])([2H])NC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O
Technical inquiry about: 17-(Allylamino-d5) Geldanamycin
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.