Product Information
Name:Ambrisentan Methyl Ester
Controlled Product
Synonyms:
- (+)-(2S)-2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic Acid Methyl Ester
- (S)-Methyl 2-((4,6-Dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate
Brand:TRC
Description:Applications (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate is a useful intermediate in the preparation of Ambrisentan. Ambrisentan is an Antihypertensive. Ambrisentan Impurity (A575860).References Peng, X., et al.: J. Org. Chem., 77, 701 (2012), Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:392.45
Formula:C23H24N2O4
Color/Form:Off-White
InChI:InChI=1S/C23H24N2O4/c1-16-15-17(2)25-22(24-16)29-20(21(26)27-3)23(28-4,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-15,20H,1-4H3/t20-/m1/s1
InChI key:InChIKey=RCOLWOXJIUGEGI-HXUWFJFHSA-N
SMILES:COC(=O)[C@@H](Oc1nc(C)cc(C)n1)C(OC)(c1ccccc1)c1ccccc1
Technical inquiry about: Ambrisentan Methyl Ester
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