9-Amino Camptothecin

CAS: 91421-43-1

Ref. TR-A603125

Product Information

• Name: 9-Amino Camptothecin
• Synonyms: (4S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 9-Amino-20(S)-camptothecin, 9-Aminocamptothecin, NSC 60307, (4S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (4S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-Amino-4(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-amino-4-ethyl-4-hydroxy-, (4S)-, 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-amino-4-ethyl-4-hydroxy-, (S)-, 9-Amino-20-(S)-camptothecin, Aminocamptothecin, NSC 603071
• CAS: 91421-43-1

Description

Applications 9-Amino Camptothecin is a derivative of Camptothecin (C175150), as antitumor agent.
References Hamadeh, H., et al.: Toxicol. Sci., 67, 219 (2002), Dolan, M., et al.: Cancer Res., 64, 4353 (2004), Antony, S., et al.: Cancer Res., 67, 10397 (2007), Pommier, Y., et al.: Mol. Cancer Ther., 8, 1008 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 363.37
• Formula: C₂₀H₁₇N₃O₄
• Color/Form: Colourless to Yellow Oil to Solid
• InChI: InChI=1S/C20H17N3O4/c1-2-20(26)13-7-16-17-10(6-11-14(21)4-3-5-15(11)22-17)8-23(16)18(24)12(13)9-27-19(20)25/h3-7,26H,2,8-9,21H2,1H3/t20-/m0/s1
• InChI key: InChIKey=FUXVKZWTXQUGMW-FQEVSTJZSA-N
• SMILES: CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(N)cccc3nc2-1