[2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone

CAS: 65514-71-8

Ref. TR-A603880

Product Information

• Name: [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone
• Synonyms: 1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine
• Brand: TRC

Description

Impurity Clozapine EP Impurity D
Applications [2-[(2-Amino-4-chlorophenyl)amino]phenyl](4-methyl-1-piperazinyl)methanone (Clozapine EP Impurity D) is used in the synthesis of substituted dibenzodiazepines. Also an impurity in the synthesis of Clozepine (C587500), an antipsychotic.
References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)

Chemical properties

• Molecular weight: 344.84
• Formula: C₁₈H₂₁ClN₄O
• Color/Form: Neat
• InChI: InChI=1S/C18H21ClN4O/c1-22-8-10-23(11-9-22)18(24)14-4-2-3-5-16(14)21-17-7-6-13(19)12-15(17)20/h2-7,12,21H,8-11,20H2,1H3
• InChI key: InChIKey=GDTYMTKNSABJKZ-UHFFFAOYSA-N
• SMILES: CN1CCN(C(=O)c2ccccc2Nc2ccc(Cl)cc2N)CC1