1-Amino-2,4-dibromo-anthraquinone

CAS: 81-49-2

Ref. TR-A604460

Product Information

• Name: 1-Amino-2,4-dibromo-anthraquinone
• Synonyms: NSC 3529, 1-Amino-2,4-dibromo-9,10-anthracenedione, 1-Amino-2,4-dibromo-9,10-anthraquinone, 1-Amino-2,4-dibromoanthraquinone, 2,4-Dibromo-1-anthraquinonylamine, 1-Amino-2,4-Dibromoanthracene-9,10-Dione, 1-Amino-2,4-dibromo-9,10-dihydroanthracene-9,10-dione, 1-Amino-2,4-dibromoanthraquinone,97%, 9,10-Anthracenedione, 1-amino-2,4-dibromo-, Anthraquinone, 1-amino-2,4-dibromo-

Description

Applications 1-Amino-2,4-dibromo-anthraquinone is a useful compound to study the uPAR·uPA protein-protein interaction (PPI) involved in signaling and proteolytic events that lead to tumor invasion and metastasis. It is also used to evaluate potential renal toxicants based on a relationship between chemical-induced kidney weight gain and kidney histopathology in rats. 1-Amino-2,4-dibromo-anthraquinone is a reagent utilized in copper-catalyzed Ullmann condensation to synthesize anthraquinone derivatives as novel dyes.
References Malik, E. M., et al.: Dyes Pigm. 131, 33 (2016); Craig, E. A., et al.: J. Appl. Toxicol. 35, 729 (2015); Mani, T., et al.: Bioorg. Med. Chem 21, 2145 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 381.02
• Formula: C₁₄H₇Br₂NO₂
• Color/Form: Neat
• InChI: InChI=1S/C14H7Br2NO2/c15-8-5-9(16)12(17)11-10(8)13(18)6-3-1-2-4-7(6)14(11)19/h1-5H,17H2
• InChI key: InChIKey=ZINRVIQBCHAZMM-UHFFFAOYSA-N
• SMILES: Nc1c(Br)cc(Br)c2c1C(=O)c1ccccc1C2=O