![7-Amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-6H-dibenz[b,d]azepin-6-one Hydrochloride](https://static.cymitquimica.com/products/TR/img/A604465.png "Click to enlarge")
7-Amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-6H-dibenz[b,d]azepin-6-one Hydrochloride
CAS: 1083065-04-6
Ref. TR-A604465
| 5mg | 160.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Product Information
Name:
7-Amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-6H-dibenz[b,d]azepin-6-one Hydrochloride
Controlled Product
Description:
Applications 7-Amino-5,7-dihydro-5-[(4-methoxyphenyl)methyl]-6H-dibenz[b,d]azepin-6-one Hydrochloride is an intermediate in the synthesis of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one, a building block for γ-secretase inhibitors for treatment of Alzheimer's disease. Several γ-secretase inhibitors have been described that contain this compound.
References Beher, D., et al.: Exp. Opin. Investig. Drugs, 14, 1385 (2005), Fauq, A., et al.: Bioorg. Med. Chem. Lett., 17, 6392 (2007),
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
344.41+(36.46)
Formula:
C22H20N2O2·HCl
Color/Form:
Neat
InChI:
InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15+/m1/s1
InChI key:
InChIKey=NWIBSHFKIJFRCO-CDOIZDJWSA-N
SMILES:
CO[C@]12[C@H](COC(N)=O)C3=C(C(=O)C(C)=C(N)C3=O)N1C[C@@H]1N[C@@H]12
MDL:
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