Product Information
Name:5-Aminoimidazole-4-carboxamide-1-Beta-D-ribofuranoside
Synonyms:
- 5-Amino-1-ribosyl-4-imidazolecarboxamide
- 5-Amino-4-imidazolecarboxamide ribofuranoside
- AIC-Riboside
- AICA-Riboside
- AICAR
- Acadesine
- Arasine
- GP 1-110
- NSC 105823,1-Ribosyl-4-carboxamido-5-aminoimidazole
Brand:TRC
Description:
Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:258.23
Formula:C9H14N4O5
Color/Form:Neat
InChI:InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N
SMILES:NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N
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