5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-13C2,15N

CAS: 1609374-70-0

Ref. TR-A611702

Product Information

• Name: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-13C2,15N
• Synonyms: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-13C2,15N, AICAR-13C2,15N, Acadesine-13C2,15N, 5-Amino-4-imidazolecarboxamide Riboside-13C2,15N, Arasine-13C2,15N, GP 1-110-13C2,15N, NSC 105823-13C2,15N
• Brand: TRC
• Description: Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Chemical properties

• Molecular weight: 261.21
• Formula: C₂C₇H₁₄₁₅NN₃O₅
• Color/Form: Neat
• InChI: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1/i4+1,7+1,12+1
• InChI key: InChIKey=RTRQQBHATOEIAF-CKEXIXISSA-N
• SMILES: NC(=O)[13c]1[15n]cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[13c]1N