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4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid
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4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid

CAS: 936890-98-1

Ref. TR-A611910

1mg
109.00 €
5mg
358.00 €
10mg
629.00 €
Estimated delivery in United States, on Thursday 20 Jun 2024

Product Information

Name:
4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid
Synonyms:
  • trans-4-[4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexanecarboxylic Acid
  • OSI 027
Description:

Applications This compound is a kinase inhibitor with anti-tumor activity, used in treatment of breast cancer. Dual mTORC1/C2 inhibitor.
References Li, H. et al.: Breast Canc. Res. Treat., 134, 1057 (2012);

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
406.44
Formula:
C21H22N6O3
Color/Form:
Pale Beige to Light Beige Solid
InChI:
InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)/t11-,12-
InChI key:
InChIKey=JROFGZPOBKIAEW-HAQNSBGRSA-N
SMILES:
COc1cccc2cc(-c3nc([C@H]4CC[C@H](C(=O)O)CC4)n4ncnc(N)c34)[nH]c12
MDL:
Melting point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TR-A611910 4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid

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