CAS 936890-98-1

Formula: C21H22N6O3

InChI: InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)

InChI key: JROFGZPOBKIAEW-UHFFFAOYSA-N

SMILES: COC1=CC=CC2=C1NC(=C2)C3=C4C(=NC=NN4C(=N3)C5CCC(CC5)C(=O)O)N

OSI-027

CAS: 936890-98-1

Formula: C₂₁H₂₂N₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 406.4378

Ref: IN-DA00GU56

Trans-4-(4-Amino-5-(7-Methoxy-1H-Indol-2-Yl)Imidazo[5,1-f][1,2,4]Triazin-7-Yl)Cyclohexanecarboxylic Acid

CAS: 936890-98-1

Trans-4-(4-Amino-5-(7-Methoxy-1H-Indol-2-Yl)Imidazo[5,1-f][1,2,4]Triazin-7-Yl)Cyclohexanecarboxylic Acid

Formula: C₂₁H₂₂N₆O₃

Purity: 98%

Molecular weight: 406.44

Ref: 54-OR1024300

OSI-027

CAS: 936890-98-1

OSI-027

Formula: C₂₁H₂₂N₆O₃

Purity: ≥95%

Molecular weight: 406.44

Ref: 54-BUP05132

OSI-027

CAS: 936890-98-1

OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.

Formula: C₂₁H₂₂N₆O₃

Purity: 97.42%

Color and Shape: Solid

Molecular weight: 406.4378

Ref: TM-T6319

OSI-027

CAS: 936890-98-1

trans-4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid

Formula: C₂₁H₂₂N₆O₃

Purity: 98%

Molecular weight: 406.44

Ref: IN-DG306064

OSI 027

CAS: 936890-98-1

OSI 027 is a monoclonal antibody that targets the BCR-ABL protein, which is found in cancer cells. OSI 027 blocks the interaction of the BCR-ABL protein with its partners, including the proteins encoded by genes such as polymerase chain and cellular transformation. OSI 027 has been shown to inhibit autophagy and induce apoptosis in cells. The drug also led to decreased enzyme activities and cell nuclei.

Formula: C₂₁H₂₂N₆O₃

Purity: Min. 95%

Molecular weight: 406.44 g/mol

Ref: 3D-FO36379