(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide Hydrochloride

CAS: 1243259-19-9

Ref. TR-A612500

Product Information

• Name: (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide Hydrochloride
• Synonyms: [S-(R*,R*)]-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide Dihydrochloride, LM11A 31 Dihydrochloride
• CAS: 1243259-19-9

Description

Stability Hygroscopic
Applications (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide is used for the preparation of peptideamides for treatment of retroviral infection. This compound has neuroprotective properties.Generally used in Alzheimers Disease, Neuroprotective, Hippocampal neural progenitors. Blood brain barrier (BBB) penetrable, orally bioactive. Blocks p75-medicated cell death.(1) Shows prominent effect against Huntington’s Disease in mice. (2)
References Simmons DA, et al. 2014. PLoS One. Aug 25;9(8):e102136Simmons DA, et al. 2016. Hum Mol Genet. Sep 16

• Brand: TRC

Chemical properties

• Molecular weight: 243.35 + 2(36.46)
• Formula: C₁₂H₂₅N₃O₂· 2HCl
• Color/Form: Neat
• InChI: InChI=1S/C12H25N3O2.2ClH/c1-3-10(2)11(13)12(16)14-4-5-15-6-8-17-9-7-15;;/h10-11H,3-9,13H2,1-2H3,(H,14,16);2*1H/t10-,11-;;/m0../s1
• InChI key: InChIKey=LLIHJRRZJDEKLB-ULEGLUPFSA-N
• SMILES: CC[C@H](C)[C@H](N)C(=O)NCCN1CCOCC1.Cl.Cl