![[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide-d4](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA618944.webp&w=3840&q=75)
Product Information
Name:[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide-d4
Controlled Product
Synonyms:
- 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide-d4
- 4-(4-Aminophenoxy)-N-methylpicolinamide-d4
- 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]aniline-d4
Brand:TRC
Description:Applications [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide-d4 is an intermediate in the synthesis of Sorafenib-d4 (S676853); a labelled version of Sorafenib (S676850), a potent RAF kinase inhibitor.References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003);Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004);Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004);Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)
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Chemical properties
Molecular weight:247.286
Formula:C13D4H9N3O2
Color/Form:Neat
InChI:InChI=1S/C13H13N3O2/c1-15-13(17)12-8-11(6-7-16-12)18-10-4-2-9(14)3-5-10/h2-8H,14H2,1H3,(H,15,17)/i2D,3D,4D,5D
InChI key:InChIKey=RXZZBPYPZLAEFC-QFFDRWTDSA-N
SMILES:[2H]c1c([2H])c(Oc2ccnc(C(=O)NC)c2)c([2H])c([2H])c1N
Technical inquiry about: [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide-d4
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