D,L-2-Amino-3-phosphonopropionic Acid

CAS: 5652-28-8

Ref. TR-A627570

Product Information

• Name: D,L-2-Amino-3-phosphonopropionic Acid
• Synonyms: 3-Phosphonoalanine, (±)-2-Amino-3-phosphonopropanoic Acid, (±)-2-Amino-3-phosphonopropionic Acid, 2-Amino-3-phosphonopropionic Acid, 3-Phosphono-DL-alanine, DL-2-Amino-2-carboxyethylphosphonic Acid, DL-2-Amino-3-phosphonopropionate, NSC 30078, (2-Amino-2-carboxyethyl)phosphonic Acid, a-Amino-ß-phosphonopropionic Acid, (±)-2-Amino-3-phosphonopropanoic acid, 2-Amino-3-phosphonopropionic acid, 3-Phosphono-<span class="text-smallcaps">DL</span>-alanine, <span class="text-smallcaps">DL</span>-2-Amino-2-carboxyethylphosphonic acid, <span class="text-smallcaps">DL</span>-2-Amino-3-phosphonopropionate, <span class="text-smallcaps">DL</span>-2-Amino-3-phosphonopropionic acid, DL-2-Amino-2-carboxyethylphosphonic acid, DL-2-Amino-3-phosphonopropionic acid, Nsc 30078, Phosphonic acid,(2-amino-2-carboxyethyl)-, a-Amino-b-phosphonopropionicacid, α-Amino-β-phosphonopropionic acid

Description

Applications D,L-2-Amino-3-phosphonopropionic acid is a phosphonate substituted derivative of Aspartic acid (A788955) and is a known antagonist of a receptor that is coupled to phosphoinositide metabolism in brain slices. D,L-2-Amino-3-phosphonopropionic acid is also an inhibitor of metabotropic glutamate receptors in rat brain.
References Hedberg, T. & Stanton, P.: Eur. J. Pharma., 310, 19 (1996); Saugstad, J., et al.: Eur. J. Pharm.: Mol. Pharm., 289, 395 (1995); Schoepp, D., et al.: Mol. Pharm., 38, 222 (1990)

• Brand: TRC

Chemical properties

• Molecular weight: 169.07
• Formula: C₃H₈NO₅P
• Color/Form: Neat
• InChI: InChI=1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)
• InChI key: InChIKey=LBTABPSJONFLPO-UHFFFAOYSA-N
• SMILES: NC(CP(=O)(O)O)C(=O)O