Product Information
Name:(3S)-Aminoquinuclidine
Controlled Product
Synonyms:
- (S)-1-Azabicyclo[2.2.2]oct-3-ylamine
- (S)-3-Amino-1-azabicyclo[2.2.2]octane
- (S)-3-Aminoquinuclidine
- (S)-Quinuclidin-3-amine
- (S)-(-)-3-Aminoquinuclidine
- (3S)-1-Azabicyclo[2.2.2]octan-3-amine
- (S)-1-Azabicyclo[2.2.2]octan-3-amine
- (3S)-1-Azabicyclo[2.2.2]octan-3-amine
Brand:TRC
Description:Applications (3S)-Aminoquinuclidine is an intermediate used in the synthesis of Palonosetron-3-ene Hydrochloride (P165825), which is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993); Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995); Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003); Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004); Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:126.2
Formula:C7H14N2
Color/Form:Neat
InChI:InChI=1S/C7H14N2/c8-7-5-9-3-1-6(7)2-4-9/h6-7H,1-5,8H2/t7-/m1/s1
InChI key:InChIKey=REUAXQZIRFXQML-SSDOTTSWSA-N
SMILES:N[C@@H]1CN2CCC1CC2
Technical inquiry about: (3S)-Aminoquinuclidine
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