α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol

CAS: 1042605-24-2

Ref. TR-A630740

Product Information

• Name: α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol
• Synonyms: 2-Amino-1-(2-(trifluoromethoxy)phenyl)ethanol

Description

Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.
References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 221.18
• Formula: C₉H₁₀F₃NO₂
• Color/Form: Neat
• InChI: InChI=1S/C9H10F3NO2/c10-9(11,12)15-8-4-2-1-3-6(8)7(14)5-13/h1-4,7,14H,5,13H2