Amiodarone

CAS: 1951-25-3

Ref. TR-A632945

Product Information

• Name: Amiodarone
• Synonyms: 2-​butyl-​3-​benzofuranyl 4-​[2-​(diethylamino)​ethoxy]​-​3,​5-​diiodophenyl Ketone, 2-​Butyl-​3-​[3,​5-​diiodo-​4-​(2-​diethylaminoethoxy)​benzoyl]​benzofuran, 2-​Butyl-​3-​benzofuranyl p-​[(2-​diethylamino)​ethoxy]​-​m,​m-​diiodophenyl ketone, 2-​n-​Butyl-​3',​5'-​diiodo-​4'-​N-​diethylaminoethoxy-​3-​benzoylbenzofuran, Amidorone, Ancaron, Sedacoron, Sedacorone, (2-Butyl-1-Benzofuran-3-Yl){4-[2-(Diethylamino)Ethoxy]-3,5-Diiodophenyl}Methanone, (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone, 2-Butyl-3-[3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl]benzofuran, 2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone, 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-n-Butyl-3′,5′-diiodo-4′-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}-N,N-diethylethanaminium chloride, Amiodaron, Amiodarona, Amiodarone Base, Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl, Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-

Description

Applications Amiodarone is a non-selective ion channel blocker. Antiarrhythmic (class III).
References Bonati, M., et al.: J. Pharm. Sci., 73, 829 (1984); Plomp, T.A., Anal. Profiles Drug Subs., 20, 1 (1991); Chow, M., et al.: Ann. Pharmacother., 30, 637 (1996), Singh, B.N., et al.: Clin. Cardiol., 20, 608 (1997)

• Brand: TRC

Chemical properties

• Molecular weight: 645.31
• Formula: C₂₅H₂₉I₂NO₃
• Color/Form: Colourless To Light Yellow
• InChI: InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3
• InChI key: InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N
• SMILES: CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1