Amlodipine Besylate

CAS: 111470-99-6

Ref. TR-A633500

Product Information

• Name: Amlodipine Besylate
• Synonyms: 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate (9CI), Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1), (±)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate, AM Arya 5, Alkapress, Alopres, Amcard, Amdepin, Amdipin, Amilo, Amlodin, Amlodin OD, Amlodipine benzenesulfonate, Amlodipine benzenesulfonate salt, Amlodis, Amlogard, Amlopers 5, Amlopin, Amlor, Amlosyn, Amlovas, Antacal, Calchek, Cardilopin, Istin, Lowrac, Monopina, Myodura, Normodipine, Norvas, Norvasc, Norvask, Regcor, Tensivask, UK 48340-26
• Brand: TRC

Description

Applications Amlodipine Besylate is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);

Chemical properties

• Molecular weight: 567.05
• Formula: C₂₀H₂₅ClN₂O₅·C₆H₆O₃S
• Color/Form: Neat
• InChI: InChI=1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)
• InChI key: InChIKey=LRVPMMZGFBZGHW-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.O=S(=O)(O)c1c[c]ccc1