Amlodipine-d4 Maleic Acid Salt (2-Chlorophenyl-d4)

CAS: 111470-99-6

Ref. TR-A633503

Product Information

• Name: Amlodipine-d4 Maleic Acid Salt (2-Chlorophenyl-d4)
• Synonyms: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl-d4)-3-ethoxycarbonyl-5-methoxycarbonyl)-6-methyl-1,4-dihydropyridine Maleic Acid Salt, (±)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate, 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl-6-Methyl-1,4-Dihydropyridine Benzenesulfonate, 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, benzenesulfonate (1:1), 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate, 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate, 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Benzenesulfonate (1:1), 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Methanesulfonate (1:1), AM Arya 5, Alkapress, Alopres, Amcard, Amdepin, Amdipin, Amilo, Amlodin, Amlodin OD, Amlodipine Besilate, Amlodipine benzenesulfonate, Amlodipine benzenesulfonate salt, Amlodis, Amlodopine Besilate, Amlogard, Amlopers 5, Amlopin, Amlor, Amlosyn, Amlovas, Antacal, Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1), Calchek, Cardilopin, Istin, Lodipressin, Lowrac, Monopina, Myodura, Normodipine, Norvas, Norvasc, Norvask, Regcor, Tensivask, Uk 48340-26, Vazkor

Description

Applications Amlodipine-d4 maleic acid salt (2-chlorophenyl-d4) is deuterium labelled amlodipine maleic acid salt (A633500), which is a calcium channel blocker.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987), Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996)

• Brand: TRC

Chemical properties

• Molecular weight: 412.9011607
• Formula: C₂₀H₂₁D₄ClN₂O₅•C₄H₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C20H25ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8,17,23H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/i5D,6D,7D,8D
• InChI key: InChIKey=TZNOWAJJWCGILX-XDWXEZNJSA-N
• SMILES: O=C(O)/C=C\C(=O)O.[2H]c1c([2H])c([2H])c(C2C(C(=O)OC)=C(C)NC(COCCN)=C2C(=O)OCC)c(Cl)c1[2H]