Ampicillin Desoxyazetidin-2-one (Mixture of Diasteromers) (~90%)

CAS: 124774-48-7

Ref. TR-A634348

Product Information

• Name: Ampicillin Desoxyazetidin-2-one (Mixture of Diasteromers) (~90%)
• Synonyms: [2R,4beta]]-2-[[(Aminophenylacetyl)amino]methyl]-5,5-dimethyl-4-thiazolidinecarboxylic Acid, (2R,4S)-2-[-Aminophenylacetyl]amino]methyl]-5,5-dimethyl-4-thiazolidinecarboxylic Acid, (2R,4S)-2-[-2-Amino-2-phenylacetyl]amino]methyl]-5,5-dimethyl-4-thiazolidinecarboxylic Acid, 4-Thiazolidinecarboxylic acid, 2-[[(aminophenylacetyl)amino]methyl]-5,5-dimethyl-, [2R-[2a(R*),4b]]-

Description

Applications Ampicillin Desoxyazetidin-2-one can be used to develop HPLC methods that detect compounds or impurities related to ampicillin in bulk drug. Ampicillin Desoxyazetidin-2-one is a related compound of Ampicillin (A634300), a β-lactam antibiotic used for treating bacterial infection. Ampicillin interferes with cell wall synthesis in bacteria.
References Raju, Ch. B. V. N., et al.: Anal Chem : Ind J, 7, 354 (2008); Fisher, J. F., et al.: Chem. Rev. 105, 395 (2005); Sill, M. L., et al.: Antimicrob. Agents Chemother. 52, 1551 (2008); Ivashkiv, E., et al.: Anal. Profiles Drug Subs. 2, 1 (1973)

• Brand: TRC

Chemical properties

• Molecular weight: 323.411
• Formula: C₁₅H₂₁N₃O₃S
• Purity: ~90%
• Color/Form: Neat
• InChI: InChI=1S/C15H21N3O3S/c1-15(2)12(14(20)21)18-10(22-15)8-17-13(19)11(16)9-6-4-3-5-7-9/h3-7,10-12,18H,8,16H2,1-2H3,(H,17,19)(H,20,21)/t10-,11?,12+/m0/s1
• InChI key: InChIKey=PIIGZYMBHCDKIJ-ASKATJPDSA-N
• SMILES: CC1(C)S[C@@H](CNC(=O)C(N)c2ccccc2)N[C@@H]1C(=O)O