Amprenavir

CAS: 161814-49-9

Ref. TR-A634400

Product Information

• Name: Amprenavir
• Synonyms: N-[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3S)-tetrahydro-3-furanyl ester, Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester (9CI), Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, tetrahydro-3-furanyl ester, [3S-[3R*(1R*,2S*)]]-, 141W94, APV, Agenerase, Angenerase, KVX 478, Prozei, Samprenavir, VX 478, VX-478, GW 433908G Fosamprenavir Calcium Test Mix 1, GW 773543, GW 569683, GW 638469, GW 638468, GW 569686, GW 783579, GW 833074, GW 634519, GW 587304, GW 461013X, 4949W94 (GW 288003X), GW 395126X, 3489W95, GW 422708X, GW 475728X, GW 327664X, GW 327662X, GW 327663X, 141W94, 141W94, KVX-478, Agenerase, Prozei,, Amprenavir & its intermediates(R&D), Carbamic acid, (1S,2R)-3-(4-aminophenyl)sulfonyl(2-methylpropyl)amino-2-hydroxy-1-(phenylmethyl)propyl-, (3S)-tetrahydro-3-furanyl ester, Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester, Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, tetrahydro-3-furanyl ester, [3S-[3R*(1R*,2S*)]]-, Kvx-478, Vx 478, tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate

Description

Applications A selective HIV protease inhibitor. An analogue of Ritonavir.
References Adkins, J.C., et al.: Drugs, 55, 837 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 505.63
• Formula: C₂₅H₃₅N₃O₆S
• Color/Form: White To Beige
• InChI: InChI=1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1
• InChI key: InChIKey=YMARZQAQMVYCKC-OEMFJLHTSA-N
• SMILES: CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1