Ampeloptin

CAS: 27200-12-0

Ref. TR-A634800

Product Information

• Name: Ampeloptin
• Synonyms: 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R,3R)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R-trans)-, Ampelopsin (6CI), Flavanone, 3,3',4',5,5',7-hexahydroxy- (7CI,8CI), (+)-Ampelopsin, (+)-Dihydromyricetin, (2R,3R)-2,3-Dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one, Ampelopsin (flavanol), Dihydromyricetin, (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one, (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R,3R)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R-trans)-, Ampelopsin, Flavanone, 3,3′,4′,5,5′,7-hexahydroxy-

Description

Stability Hygroscopic
Applications Ampeloptin is an antioxidant and a competitive GABAA antagonist (1,2,3). Ampeloptin competitively inhibits the benzodiazepine site and induces autophagy and shows antiproliferative effects.
References (1) Xia, J., et al.: Food Chem. Toxicol., 66, 7 (2014) (2) Shen, Y., et al.: J. Neurosci., 32, 390 (2012) (3) Zhang, Y., et al.: Yao Xue Xue Bao, 38, 241 (2003)

• Brand: TRC

Chemical properties

• Molecular weight: 320.25
• Formula: C₁₅H₁₂O₈
• Color/Form: Beige
• InChI: InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
• InChI key: InChIKey=HLLGFGBLKOIZOM-UHFFFAOYSA-N
• SMILES: O=CC(c1ccccc1)c1ccccc1