Product Information
Name:2,5-Anhydro-2,5-imino-D-glucitol
Controlled Product
Synonyms:
- (2R,3R,4R,5S)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
Brand:TRC
Description:Applications Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and are believed to associate with acidic amino acids at the active site. Inhibition of glycohydrolases could be of therapeutic value for the treatment of viral infections, cancer, diabetes, and obesity.References Fellows, L.E., et al.: J. Chem. Brit., 287, (1987), Elbein, A.D.: Annu. Rev. Biochem., 56, 497 (1987), Fleet, G.W., et al.: J. Chem. Brit., 287, (1989) Baxter, E.W., et al.: J. Org. Chem., 59, 3175 (1994); Tyms, A.S. et al. Lancet 1025, (1987); Spearman, M.A. et al. Expt. Cell Res. 168, 116 (1987); Horii, S. et al. J. Med. Chem. 29, 1038 (1986).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:163.17
Formula:C6H13NO4
Color/Form:Neat
InChI:InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI key:InChIKey=PFYHYHZGDNWFIF-JMSAOHGTSA-N
SMILES:OC[C@@H]1N[C@H](CO)C(O)[C@@H]1O
Technical inquiry about: 2,5-Anhydro-2,5-imino-D-glucitol
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