Anhydrotetracycline Hydrochloride

CAS: 13803-65-1

Ref. TR-A656050

Product Information

• Name: Anhydrotetracycline Hydrochloride
• Synonyms: 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride, (4S,4aS,12aS)- (9CI), 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride (8CI), 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride, [4S-(4펱,4a펱,12a펱)]-, Chlortetracycline Hydrochloride Impurity J as Hydrochloride, Tetracycline Hydrochloride Impurity C as Hydrochloride, Chlortetracycline Impurity J as Hydrochloride
• Brand: TRC
• Description: Impurity Tetracycline EP Impurity C HydrochlorideStability HygroscopicApplications Anhydrotetracycline is a tetracycline derivative exhibiting no antibiotic activity, a useful effector of tetracycline-dependent gene expression in bacterial expression systems. It is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR systems, binding the Tet(R).References Sokoloski, T., et al.: J. Pharm. Sci., 66, 1159 (1977), Paemen, L., et al.: Biochem. Pharmacol., 5, 105 (1996); A. Kamionka, et al.; Nucleic Acids Res. 32, 842 (2004) | M. Resch, et al.; Nucleic Acids Res. 36, 4390 (2008)

Chemical properties

• Molecular weight: 462.88
• Formula: C₂₂H₂₂N₂O₇·HCl
• Color/Form: Yellow
• InChI: InChI=1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16-,22-;/m0./s1
• InChI key: InChIKey=XBSQEFHDCDFNJU-WPJNXPDPSA-N
• SMILES: Cc1c2c(c(O)c3c(O)cccc13)C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]1C2.Cl