Antibiotic A21 (Technical Grade)

CAS: 1383659-59-3

Ref. TR-A697440

Product Information

• Name: Antibiotic A21 (Technical Grade)
• Synonyms: Amphotericin A21 Molecule, L-Histidine, Methyl Ester, Amide With Amphotericin B
• Brand: TRC
• Description: Stability Temperature SensitiveApplications Antibiotic A21 is a new polyene macrolide Amphotericin amide antibiotic with antimycotic effectiveness.References Flores-Romero, J. D., et al.: Org. Process Res. Dev., 20, 1529 (2016), Antillon, A., et al.: PLoS One, 11, 9 (2016)

Chemical properties

• Molecular weight: 1075.24
• Formula: C₅₄H₈₂N₄O₁₈
• Color/Form: Neat
• InChI: InChI=1S/C54H82N4O18/c1-31-18-16-14-12-10-8-6-7-9-11-13-15-17-19-39(75-53-50(68)47(55)49(67)34(4)74-53)26-44-46(51(69)58-40(52(70)72-5)22-35-29-56-30-57-35)43(64)28-54(71,76-44)27-38(61)24-42(63)41(62)21-20-36(59)23-37(60)25-45(65)73-33(3)32(2)48(31)66/h6-19,29-34,36-44,46-50,53,59-64,66-68,71H,20-28,55H2,1-5H3,(H,56,57)(H,58,69)/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t31-,32-,33-,34+,36+,37+,38-,39-,40-,41+,42+,43-,44-,46+,47-,48+,49+,50-,53-,54+/m0/s1
• InChI key: InChIKey=HYLVVIVHCVMQGE-BOTNPQSTSA-N
• SMILES: COC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1[C@@H](O)C[C@@]2(O)C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)C[C@@H]1O2