Aquavan

CAS: 258516-87-9

Ref. TR-A735445

Product Information

• Name: Aquavan
• Synonyms: 1-[2,6-bis(1-methylethyl)phenoxy]methanol 1-(Dihydrogen phosphate) Disodium Salt, [2,6-Bis(1-methylethyl)phenoxy]methanol Dihydrogen Phosphate Disodium Salt, Aqavan Injection, Fospropofol Disodium, GPI 15715, Lusedra, Aquavan injection, Disodium [2,6-Bis(1-Methylethyl)Phenoxy]Methyl Phosphate, Fospropofol Disodium (Aquavan), Gpi 15715, Methanol, (2,6-bis(1-methylethyl)phenoxy)-, dihydrogen phosphate, disodium salt, Methanol, 1-[2,6-bis(1-methylethyl)phenoxy]-, 1-(dihydrogen phosphate), sodium salt (1:2), Pq-1002, Unii-30868Ay0If

Description

Stability Hygroscopic
Applications Aquavan, more commonly known as Fospropofol Disodium, is a sedative/ hypnotic drug and a water-soluble prodrug of Propofol (P829750). Studies show that Fospropofol Disodium can have a protective effect on rat liver against ischemia-reperfusion injury.
References Campion, M.E., et al.: Drugs Today, 45, 567 (2009); Liu, Y., et al.: Sichuan Daxue Xuebao, Yixueban, 42, 231 (2011); Wang, H., et al.: Yiyao Daobao, 29, 1291 (2010); Xie, L., et al.: Mazui Yu Jianhu Luntan, 17, 348 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 332.24
• Formula: C₁₃H₁₉Na₂O₅P
• Color/Form: Neat
• InChI: InChI=1S/C13H21O5P.2Na/c1-9(2)11-6-5-7-12(10(3)4)13(11)17-8-18-19(14,15)16;;/h5-7,9-10H,8H2,1-4H3,(H2,14,15,16);;/q;2*+1/p-2
• InChI key: InChIKey=LWYLQNWMSGFCOZ-UHFFFAOYSA-L
• SMILES: CC(C)c1cccc(C(C)C)c1OCOP(=O)(O[Na])O[Na]