Estimated delivery in United States, on Friday 10 Jan 2025
Product Information
Name:
Aramchol
Controlled Product
Synonyms:
- (3ß,5ß,7a,12a)-7,12-Dihydroxy-3-[(1-oxoeicosyl)amino]-cholan-24-oic Acid
- (3ß)-Arachidylamido-7a,12a-dihydroxy-5ß-cholan-24-oic Acid
- C20-FABAC
- (3β)-Arachidylamido-7α,12α-dihydroxy-5β-cholan-24-oic acid
- (3β,5β,7α,12α)-7,12-Dihydroxy-3-[(1-oxoeicosyl)amino]cholan-24-oic acid
- (4R)-4-[(3S,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-3-(icosanoylamino)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
- C<sub>20</sub>-FABAC
- Cholan-24-oic acid, 7,12-dihydroxy-3-[(1-oxoeicosyl)amino]-, (3β,5β,7α,12α)-
Description:
Applications Aramchol is a fatty acid conjugate that exhibits hypocholesterolemic effects. Studies have shown that aramchol suppresses the activity of stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.
References Leikin-Frenkel, A., et al.: Arch Med Res. 41, 397 (2010); Gonen, A., et al.: Pathobiology 70, 215 (2003)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
702.1
Formula:
C44H79NO5
Color/Form:
Neat
InChI:
InChI=1S/C44H79NO5/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-40(48)45-34-27-28-43(3)33(29-34)30-38(46)42-36-25-24-35(32(2)23-26-41(49)50)44(36,4)39(47)31-37(42)43/h32-39,42,46-47H,5-31H2,1-4H3,(H,45,48)(H,49,50)/t32-,33+,34+,35-,36+,37+,38-,39+,42+,43+,44-/m1/s1
InChI key:
InChIKey=SHKXZIQNFMOPBS-OOMQYRRCSA-N
SMILES:
CCCCCCCCCCCCCCCCCCCC(=O)N[C@H]1CC[C@@]2(C)[C@@H](C1)C[C@@H](O)[C@@H]1[C@@H]2C[C@H](O)[C@@]2(C)[C@H]1CC[C@@H]2[C@H](C)CCC(=O)O
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-A765150 Aramchol
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