Product Information
Name:Aramchol
Controlled Product
Synonyms:
- (3β,5β,7α,12α)-7,12-Dihydroxy-3-[(1-oxoeicosyl)amino]-cholan-24-oic Acid
- (3β)-Arachidylamido-7α,12α-dihydroxy-5β-cholan-24-oic Acid
- C20-FABAC
Brand:TRC
Description:Applications Aramchol is a fatty acid conjugate that exhibits hypocholesterolemic effects. Studies have shown that aramchol suppresses the activity of stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.References Leikin-Frenkel, A., et al.: Arch Med Res. 41, 397 (2010); Gonen, A., et al.: Pathobiology 70, 215 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:702.1
Formula:C44H79NO5
Color/Form:Neat
InChI:InChI=1S/C44H79NO5/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-40(48)45-34-27-28-43(3)33(29-34)30-38(46)42-36-25-24-35(32(2)23-26-41(49)50)44(36,4)39(47)31-37(42)43/h32-39,42,46-47H,5-31H2,1-4H3,(H,45,48)(H,49,50)/t32-,33+,34+,35-,36+,37+,38-,39+,42+,43+,44-/m1/s1
InChI key:InChIKey=SHKXZIQNFMOPBS-OOMQYRRCSA-N
SMILES:CCCCCCCCCCCCCCCCCCCC(=O)N[C@H]1CC[C@@]2(C)[C@@H](C1)C[C@@H](O)[C@@H]1[C@@H]2C[C@H](O)[C@@]2(C)[C@H]1CC[C@@H]2[C@H](C)CCC(=O)O
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