Product Information
Name:AR-AO 14418
Controlled Product
Synonyms:
- AR 0133418
- GSK 3B Inhibitor VIII
Brand:TRC
Description:
Applications AR-AO 14418 is a glycogen synthase kinase 3β (GSK-3β) inhibitor (1,2,3). GSK-3β is a serine/threonine protein kinase that is involved numerous diseases such as type II diabetes and Alzheimer's.
References (1) Koh, S., et al.:Toxicol., 247, 112 (2008) (2) Vadivelan, S., et al.: Eur. J. Med. Chem., 44, 2361 (2009) (3) Min, W., et al.: Neuropharmacol., 56, 463 (2009)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:308.31
Formula:C12H12N4O4S
Color/Form:Neat
InChI:InChI=1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)
SMILES:COc1ccc(CNC(=O)Nc2ncc([N+](=O)[O-])s2)cc1
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