Aripiprazole

CAS: 129722-12-9

Ref. TR-A771000

Product Information

• Name: Aripiprazole
• Synonyms: 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone, 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril, Abilify, Abilitat, Arpizol, Asprito, OPC 14597, OPC 31, Pripiprazole, 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-, 7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]Butoxy]-3,4-Dihydrocarbostyril, 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one, Aripiperazole, Aripiprazol, Aripiprizole, Aripirazole, Aristab, Biopiprazole, Opc 14597, Opc 31

Description

Applications Aripiprazole is an agonist at the dopamine autoreceptor and an antagonist at the postsynaptic D2 receptor (1,2,3,4). Aripiprazole is an antipsychotic and a potential drug candidate for treating psychoses such as schizophrenia.
References (1) Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998)(2) Shiokawa, M., et al.: Eur.J.Pharmacol. 570, 108 (2007)(3) Oshiro, Y., et al.: J. Med. Chem. 41, 658 (1998)(4) Ozdemir, V., et al.: Curr Opin Investig Drugs. 3, 113 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 448.39
• Formula: C₂₃H₂₇Cl₂N₃O₂
• Color/Form: Off-White
• InChI: InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
• InChI key: InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N
• SMILES: O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1