R-(-)-Arundic Acid

CAS: 185517-21-9

Ref. TR-A779500

Product Information

• Name: R-(-)-Arundic Acid
• Synonyms: (2R)-2-propyloctanoic acid, Arundic acid, Ono-2506Po, Ono-2506, Proglia, Cereact, 2-Propyloctanoic Acid

Description

Applications An astrocyte modulating agent, in acute ischemic stroke. A therapeutic agent for the treatment of neurodegenerative diseases including Alzheimer's disease and Parkinson’s disease. This compound has neuroprotective properties. Also used in Glaucoma Research. Inhibits secondary injury and improves motor function in rats with spinal cord injury (1). Inhibits the production and release of S100 protein from astrocytes. Stimulates the human GLAST ortholog, EAAT1, expression in human neuroglioblastoma cells (2).
References Hanada M, et al. 2014. J Neurol Sci. 15;337(1-2):186-92. Yanagisawa M, et al. 2015. Cell Death Dis. 19;6:e1693

• Brand: TRC

Chemical properties

• Molecular weight: 186.29
• Formula: C₁₁H₂₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C11H22O2/c1-3-5-6-7-9-10(8-4-2)11(12)13/h10H,3-9H2,1-2H3,(H,12,13)/t10-/m1/s1
• InChI key: InChIKey=YCYMCMYLORLIJX-SNVBAGLBSA-N
• SMILES: CCCCCC[C@@H](CCC)C(=O)O