Asenapine

CAS: 65576-45-6

Ref. TR-A788000

Product Information

• Name: Asenapine
• Synonyms: (3aR,12bR)-rel-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, trans-, Saphris, Sycrest, (3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole, (3aS,12bS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole, 1H-Dibenz(2,3:6,7)oxepino(4,5-c)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, (3aR,12bR)-rel-, 1H-Dibenz(2,3:6,7)oxepino(4,5-c)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, trans-, Alkepin, Asenapine [INN:BAN], Org 5222, Unii-Jkz19V908O, rel-(3aR,12bR)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole

Description

Applications Combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Antipsychotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989), Schotte, A., et al.: Brain Res., 631, 191 (1993), Andree, B., et al.: Psychopharmacology, 131, 339 (1997), Richelson, E., et al.: Life Sci., 68, 29 (2000),

• Brand: TRC

Chemical properties

• Molecular weight: 285.77
• Formula: C₁₇H₁₆ClNO
• Color/Form: Neat
• InChI: InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3/t14-,15-/m0/s1
• InChI key: InChIKey=VSWBSWWIRNCQIJ-HUUCEWRRSA-N
• SMILES: CN1C[C@@H]2c3ccccc3Oc3ccc(Cl)cc3[C@H]2C1