Atazanavir-d5

CAS: 1132747-14-8

Ref. TR-A790052

Product Information

• Name: Atazanavir-d5
• Synonyms: 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-dimethyl Ester, (3S,8S,9S,12S)-2,5,6,13-Pentaazatetradecanedioic Acid-d5, BMS-232632-d5, CGP-73547-d5

Description

Applications Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Newer research has been investigating the potential anticancer effects of atazanavir
References Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998), Nolan, D., et al.: Drugs, 63(23), 2555 (2003), Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 709.89
• Formula: C₃₈H₄₇D₅N₆O₇
• Color/Form: Neat
• InChI: InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32-/m0/s1/i9D,10D,11D,14D,15D
• InChI key: InChIKey=AXRYRYVKAWYZBR-YZACTSSDSA-N
• SMILES: [2H]c1c([2H])c([2H])c(C[C@H](NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)[C@@H](O)CN(Cc2ccc(-c3ccccn3)cc2)NC(=O)[C@H](NC(=O)OC)C(C)(C)C)c([2H])c1[2H]