Atorvastatin-d5 Sodium Salt

CAS: 222412-87-5

Ref. TR-A791752

Product Information

• Name: Atorvastatin-d5 Sodium Salt
• Synonyms: 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-, monosodium salt, (βR,δR)- (9CI), (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-(phenyl-d5)-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid sodium salt, (βR,δR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-(phenyl-d5)-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid sodium salt, Atorvastatin-D5 sodium salt (3-phenyl-D5)
• Brand: TRC
• Description: Stability HygroscopicApplications A deuterated selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),

Chemical properties

• Molecular weight: 585.65
• Formula: C₃₃₂H₅H₂₉FN₂O₅·Na
• Purity: >90%
• Color/Form: Off-White To Light Brown
• InChI: InChI=1S/C33H35FN2O5.Na/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;+1/p-1/t26-,27-;/m1./s1/i3D,5D,6D,9D,10D
• InChI key: InChIKey=VVRPOCPLIUDBSA-ADFDHUHVSA-M
• SMILES: [2H]c1c([2H])c([2H])c(-c2c(C(=O)Nc3ccccc3)c(C(C)C)n(CC[C@@H](O)C[C@@H](O)CC(=O)O[Na])c2-c2ccc(F)cc2)c([2H])c1[2H]