Atorvastatin Epoxy Pyrrolooxazin Tricyclic Potassium Salt Impurity (>85%)

Ref. TR-A791895

Product Information

• Name: Atorvastatin Epoxy Pyrrolooxazin Tricyclic Potassium Salt Impurity (>85%)
• Synonyms: Atorvastatin Impurity, Sodium 2-(9-(4-Fluorophenyl)-1b-isopropyl-9a-phenyl-1a-(phenylcarbamoyl)octahydro-1aH-5,9-epoxyoxireno[2',3':3,4]pyrrolo[2,1-b][1,3]oxazocin-3-yl)acetate
• Brand: TRC
• Description: Applications A photodegadation product of Atorvastatin (a cyclic impurity of Atorvastatin (A791750)), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),

Chemical properties

• Molecular weight: 610.714
• Formula: C₃₃H₃₂FKN₂O₆
• Purity: >85%
• Color/Form: Neat
• InChI: InChI=1S/C33H33FN2O6.K/c1-21(2)32-31(29(39)35-25-11-7-4-8-12-25)30(42-31,22-9-5-3-6-10-22)33(23-13-15-24(34)16-14-23)36(32)18-17-26(40-33)19-27(41-32)20-28(37)38;/h3-16,21,26-27H,17-20H2,1-2H3,(H,35,39)(H,37,38);/q;+1/p-1
• InChI key: InChIKey=GCAVIWLLCOMUJX-UHFFFAOYSA-M
• SMILES: CC(C)C12OC(CC(=O)O[K])CC3CCN1C(c1ccc(F)cc1)(O3)C1(c3ccccc3)OC21C(=O)Nc1ccccc1