Aureusimine B

CAS: 170713-71-0

Ref. TR-A794570

Product Information

• Name: Aureusimine B
• Synonyms: 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone, Phevalin

Description

Applications Aureusimine B is a novel small molecule isolated from S. aureus as one of a pair of related metabolites controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B has also been reported as an inhibitor of the protease, calpain.
References Archer, G., et al.: Clin. Infect. Dis., 26, 1179 (1998); Novick, R., et al.: Mol. Microbiol., 48, 1429 (2003); Liang, X., et al.: Infect. Immun., 74, 4655 (2006); Geiger, T., et al.: J. Bacteriol., 190, 3419 (2008);

• Brand: TRC

Chemical properties

• Molecular weight: 228.29
• Formula: C₁₄H₁₆N₂O
• Color/Form: Off-White To Grey
• InChI: InChI=1S/C14H16N2O/c1-10(2)13-14(17)16-12(9-15-13)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,16,17)
• InChI key: InChIKey=CZUORGWXUVRUMV-UHFFFAOYSA-N
• SMILES: CC(C)c1ncc(Cc2ccccc2)[nH]c1=O