Avibactam Sodium Salt

CAS: 1192491-61-4

Ref. TR-A794850

Product Information

• Name: Avibactam Sodium Salt
• Synonyms: Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester, sodium salt (1:1), Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester monosodium salt, (1R,2S,5R)-7-Oxo-6-sulfooxy-1,6-diazabicyclo[3.2.1]octane-2-carboxamide sodium salt, Avibactam sodium, (2S,5R)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide monosodium salt, Avibactam Sodium, Nxl 104, Sulfuric acid Mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester sodium salt, Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester, sodium salt (1:1)

Description

Applications Avibactam (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold. NXL104 irreversibly inhibits lactamase from Mycobacterium tuberculosis.
References Iland, C., et al.: J. Pathol. Bacteriol., 58, 495 (1946), Flores, A., et al.: Microbiology, 151, 521 (2005), Livermore, D., et al.: J. Antimicrob. Chemother., 62, 1053 (2008), Tremblay, L., et al.: Biochemistry, 49, 9685 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 287.23
• Formula: C₇H₁₀N₃O₆S·Na
• Color/Form: Neat
• InChI: InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
• SMILES: NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(=O)(=O)[O-].[Na+]