6-Azauridine Triacetate

CAS: 2169-64-4

Ref. TR-A805110

Product Information

• Name: 6-Azauridine Triacetate
• Synonyms: 2-(2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, 2',3',5'-Tri-O-acetyl-6-azauridine, 6-Aza-2',3',5'-tri-O-acetyluridine, Azaribin, Azaribine, CB 304, NSC 67239, Triazure, 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, 2,3,5-Tri-O-acetyl-6-azauridine, 2-(2,3,5-Tri-O-acetyl-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetylpentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2,3,5-triacetate, 6-Aza-2′,3′,5′-tri-O-acetyluridine, 6-Azauridine triacetate, Cb 304, as-Triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 2′,3′,5′-triacetate, 2-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, as-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-, 2′,3′,5′-triacetate, 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-

Description

Applications 6-Azauridine Triacetate is used in the preparation of potential 3-deazauridine and 6-azauridine prodrugs through enzymic alcoholysis, active antiviral compound against new york isolate of West Nile virus.
References Zinni, M. A., et al.: Journal of Molecular Catalysis B: Enzymatic, J. Mol., 47, 86 (2007); Morrey, J. D., et al.: Antiviral Res., 55, 107 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 371.3
• Formula: C₁₄H₁₇N₃O₉
• Color/Form: Neat
• InChI: InChI=1S/C14H17N3O9/c1-6(18)23-5-9-11(24-7(2)19)12(25-8(3)20)13(26-9)17-14(22)16-10(21)4-15-17/h4,9,11-13H,5H2,1-3H3,(H,16,21,22)/t9-,11-,12-,13-/m1/s1
• InChI key: InChIKey=QQOBRRFOVWGIMD-OJAKKHQRSA-N
• SMILES: CC(=O)OC[C@H]1O[C@@H](n2ncc(=O)[nH]c2=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O