Azoxydapsone

CAS: 35040-12-1

Ref. TR-A965135

Product Information

• Name: Azoxydapsone
• Synonyms: 4,4'-[Azoxybis(4,1-phenylenesulfonyl)]bisbenzenamine, 4,4'-Disulfanilylazoxybenzene, 4,4'-Bis(p-aminobenzenesulfonyl)azoxybenzene

Description

Applications Azoxydapsone is a primary urinary N-oxidation metabolite of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.
References Israili, Z.H., et al.: J. Pharmacol. Exp. Ther., 187, 138 (1973); Cucinell, S.A., et al.: Am. J. Trop. Med. Hyg., 21, 322 (1972); Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)

• Brand: TRC

Chemical properties

• Molecular weight: 508.57
• Formula: C₂₄H₂₀N₄O₅S₂
• Color/Form: Neat
• InChI: InChI=1S/C24H20N4O5S2/c25-17-1-9-21(10-2-17)34(30,31)23-13-5-19(6-14-23)27-28(29)20-7-15-24(16-8-20)35(32,33)22-11-3-18(26)4-12-22/h1-16H,25-26H2/b28-27-
• InChI key: InChIKey=SMEWQWPADHSEIL-DQSJHHFOSA-N
• SMILES: Nc1ccc(S(=O)(=O)c2ccc(N=[N+]([O-])c3ccc(S(=O)(=O)c4ccc(N)cc4)cc3)cc2)cc1