Product Information
Name:
AZD-2098
Synonyms:
- ,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide
- AZD2098
Description:
Applications AZD-2098 is a potent and selective agonist of CCR4 chemokine receptor with IC50 values ranging from 10 to 25 nM across different species. CCR4 is involved in activation and migration of Th2 lymphocytes to the lungs in response to allergens. Treating sensitised rats results in reduced inflammation of lung tissue.
References Kindon, Nicholas., et al.: ACS Med Chem Lett., 8, 981 (2017),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
334.18
Formula:
C11H9Cl2N3O3S
Color/Form:
Off-White to Pale Yellow Solid
InChI:
InChI=1S/C11H9Cl2N3O3S/c1-19-11-10(14-5-6-15-11)16-20(17,18)8-4-2-3-7(12)9(8)13/h2-6H,1H3,(H,14,16)
InChI key:
InChIKey=FLSMVCMSUNISFK-UHFFFAOYSA-N
SMILES:
COc1nccnc1NS(=O)(=O)c1cccc(Cl)c1Cl
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