CAS 566203-88-1

AZD2098

Description:

AZD2098, with the CAS number 566203-88-1, is a chemical compound that has been investigated primarily for its potential therapeutic applications. It is classified as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4), which plays a crucial role in the regulation of inflammatory processes and immune responses. The inhibition of PDE4 can lead to increased levels of cyclic AMP (cAMP) within cells, thereby modulating various signaling pathways associated with inflammation and immune function. AZD2098 has shown promise in preclinical studies for conditions such as chronic obstructive pulmonary disease (COPD) and asthma, where inflammation is a key factor. The compound's pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile in clinical settings. As with many investigational drugs, ongoing research is necessary to fully elucidate its mechanism of action, therapeutic potential, and any associated side effects.

Formula: C₁₁H₉Cl₂N₃O₃S

InChI: InChI=1S/C11H9Cl2N3O3S/c1-19-11-10(14-5-6-15-11)16-20(17,18)8-4-2-3-7(12)9(8)13/h2-6H,1H3,(H,14,16)

InChI key: FLSMVCMSUNISFK-UHFFFAOYSA-N

SMILES: COC1=NC=CN=C1NS(=O)(=O)C2=C(C(=CC=C2)Cl)Cl

Synonyms:

• Benzenesulfonamide, 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)-
• AZD-2098 >=98% (HPLC)
• AZD 2098 NEW
• 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide
• AZD2098
• AZD 2098;AZD-2098;AZD2098

2,3-Dichloro-N-(3-Methoxypyrazin-2-Yl)Benzenesulfonamide

CAS: 566203-88-1

2,3-Dichloro-N-(3-Methoxypyrazin-2-Yl)Benzenesulfonamide

Formula: C₁₁H₉Cl₂N₃O₃S

Purity: 99%

Molecular weight: 334.18

Ref: 54-OR1024271

AZD2098

CAS: 566203-88-1

AZD2098

Formula: C₁₁H₉Cl₂N₃O₃S

Purity: ≥98%

Molecular weight: 334.18

Ref: 54-BUP12876

AZD-2098

CAS: 566203-88-1

Formula: C₁₁H₉Cl₂N₃O₃S

Purity: %

Color and Shape: Solid

Molecular weight: 334.1785

Ref: IN-DA01EAB7

AZD2098

CAS: 566203-88-1

AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.

Formula: C₁₁H₉Cl₂N₃O₃S

Purity: 99.75% - 99.94%

Color and Shape: Solid

Molecular weight: 334.178

Ref: TM-T4300

AZD 2098

CAS: 566203-88-1

A potent and selective agonist of CCR4 chemokine receptor with IC50 values ranging from 10 to 25 nM across different species. CCR4 is involved in activation and migration of Th2 lymphocytes to the lungs in response to allergens. Treating sensitised rats results in reduced inflammation of lung tissue.

Formula: C₁₁H₉Cl₂N₃O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 334.18 g/mol

Ref: 3D-BA163812

AZD2098

CAS: 566203-88-1

2,3-Dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide

Formula: C₁₁H₉Cl₂N₃O₃S

Purity: 99%

Molecular weight: 334.18

Ref: IN-DG768451

2,3-DICHLORO-N-(3-METHOXYPYRAZIN-2-YL)BENZENESULFONAMIDE

CAS: 566203-88-1

Purity: 98+%

Molecular weight: 334.1700134

Ref: 10-F818654