Product Information
Name:BAY 41-2272
Controlled Product
Synonyms:
- 5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
Brand:TRC
Description:Applications BAY 41-2272 is a soluble guanylate cyclase agonist that activates human mononuclear phagocytes. Inhibits vascular smooth muscle growth through the cAMP-dependent protein kinase and cGMP-dependent protein kinase pathways.References Soeiro-Pereira, P. et al.: British. J. Pharmacol., 166, 1617 (2012); Joshi, C. et al.: J. Pharmacol. Exp. Ther., 339, 394 (2011)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:360.39
Formula:C20H17FN6
Color/Form:Neat
InChI:InChI=1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25)
InChI key:InChIKey=ATOAHNRJAXSBOR-UHFFFAOYSA-N
SMILES:Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ncc1C1CC1
Technical inquiry about: BAY 41-2272
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