Benazepril tert-Butyl Ester

CAS: 109010-61-9

Ref. TR-B119850

Product Information

• Name: Benazepril tert-Butyl Ester
• Synonyms: 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, 1,1-dimethylethyl ester, [S-(R*,R*)]-, 1,1-Dimethylethyl (3S)-3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetate, Benazepril tert-Butyl Ester,1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, 1,1-dimethylethyl ester, (3S)-
• Brand: TRC
• Description: Applications Benazepril tert-Butyl Ester is a useful synthetic intermediate in the synthesis of Benazepril Hydrochloride (B119750); a potent angiotensin converting enzyme (ACE) inhibitor and antihypertensive.References Kafssi, H., et al.: Huaxue Shiji, 29, 371 (2007); Chang, C.Y., et al.: Tetrahedron-Assymetr., 14, 2239 (2003); Schaller, M.D., et al.: Eur. J. Clin. Pharmacol., 28, 267 (1985); Colfer, H.T., et al.: Am. J. Cardiol., 70, 354 (1992)

Chemical properties

• Molecular weight: 480.6
• Formula: C₂₈H₃₆N₂O₅
• Color/Form: Neat
• InChI: InChI=1S/C28H36N2O5/c1-5-34-27(33)23(17-15-20-11-7-6-8-12-20)29-22-18-16-21-13-9-10-14-24(21)30(26(22)32)19-25(31)35-28(2,3)4/h6-14,22-23,29H,5,15-19H2,1-4H3/t22-,23-/m0/s1
• InChI key: InChIKey=QNLLWVSHZXSUNF-GOTSBHOMSA-N
• SMILES: CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(=O)OC(C)(C)C)C1=O