Beclomethasone

CAS: 4419-39-0

Ref. TR-B131000

Product Information

• Name: Beclomethasone
• Synonyms: 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione, Beclometasone, CCI 2332, 9-Chloro-11ß,17,21-trihydroxy-16ß-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 9-chloro-11ß,17,21-trihydroxy-16ß-methyl- (7CI,8CI), (11ß,16ß)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9-Chloro-11ß,17,21-trihydroxy-16ß-methyl-pregna-1,4-diene-3,20-dione, 9-Chloro-16ß-methylprednisolone, 9a-Chloro-16ß-methylprednisolone, Beclometasone, Becolvent, (11β,16β)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, (8S,10S,11S,13S,16S)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, 4419-39-0, 9-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate, 9-Chloro-11β,17,21-trihydroxy-16β-methyl-pregna-1,4-diene-3,20-dione, 9-Chloro-16β-methylprednisolone, 9α-Chloro-16β-methylprednisolone, Beclometason, Beclometasona, Beclometasone 17,21-Dipropionate, Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-chloro-11β,17,21-trihydroxy-16β-methyl-

Description

Stability Hygroscopic
Applications Glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).
References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),

• Brand: TRC

Chemical properties

• Molecular weight: 408.92
• Formula: C₂₂H₂₉ClO₅
• Color/Form: Off-White
• InChI: InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI key: InChIKey=NBMKJKDGKREAPL-IGAOFSIFSA-N
• SMILES: C[C@H]1C[C@@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@]1(O)C(=O)CO