Product Information
Name:2-Benzamido-1,4-naphthoquinone
Controlled Product
Synonyms:
- N-(1,4-Dihydro-1,4-dioxo-2-naphthalenyl)benzamide
- N-(1,4-Dioxo-1,4-dihydronaphthalen-2-yl)benzamide
- NSC 73233
- PPM 18
Brand:TRC
Description:Applications 2-Benzamido-1,4-naphthoquinone belongs to a novel class of small molecule inhibitors of histone deacetylase (HDAC6), a family of enzymes that play significant role in numerous biological processes and diseases. 2-Benzamido-1,4-naphthoquinone was also shown to be an activation blocker of nuclear factor-kB (NF-kB).References Inks, E.S., et al.: ACS. Chem. Biol., 7, 331 (2012); Lien, J.C., et al.: Chem. Pharma. Bull.. 44. 1181 (1996);
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Chemical properties
Molecular weight:277.27
Formula:C17H11NO3
Color/Form:Neat
InChI:InChI=1S/C17H11NO3/c19-15-10-14(16(20)13-9-5-4-8-12(13)15)18-17(21)11-6-2-1-3-7-11/h1-10H,(H,18,21)
InChI key:InChIKey=BIVQBWSIGJFXLF-UHFFFAOYSA-N
SMILES:O=C(NC1=CC(=O)c2ccccc2C1=O)c1ccccc1
Technical inquiry about: 2-Benzamido-1,4-naphthoquinone
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