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N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate

CAS:

Ref. TR-B206670

N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate
TRC

    Product Information

    Name:N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate
    Controlled Product
    Synonyms:
    • N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyO-phenylCarbamate
    Brand:TRC
    Description:

    Applications N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate is an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Zileuton is used as an antiasthmatic.
    References Carter, G.W., et al.: J. Pharmacol. Exp. Ther., 256, 929 (1991); Weinblatt, M.E., et al.: J. Rheumatol., 19, 1537 (1992); McGill, K and Busse, W.W.: Lancet, 348, 519 (1996)

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    Chemical properties

    Molecular weight:313.37
    Formula:C17H15NO3S
    Color/Form:Neat
    InChI:InChI=1S/C17H15NO3S/c1-12(16-11-13-7-5-6-10-15(13)22-16)18(20)17(19)21-14-8-3-2-4-9-14/h2-12,20H,1H3
    InChI key:InChIKey=JTKHUJNVHQWSAY-UHFFFAOYSA-N
    SMILES:CC(C)CCCCCCCCO

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