N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine

CAS: 251647-48-0

Ref. TR-B207900

Product Information

• Name: N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine
• Synonyms: N-(9-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide, N-Benzoyl-5’-O-DMTR-2’-O-(2-methoxyethyl)-adenosine, 17: PN: US20030211606 PAGE: 19 claimed sequence, 18: PN: US20040005569 PAGE: 22 claimed sequence, 20: PN: US20040006030 PAGE: 23 claimed sequence, 20: PN: US20040014047 PAGE: 21 claimed sequence, 20: PN: US20040014049 PAGE: 21 claimed sequence, 21: PN: US20040005570 PAGE: 20 claimed sequence, 21: PN: US20040014048 PAGE: 21 claimed sequence, 21: PN: US20040014050 PAGE: 20 claimed sequence, 22: PN: US20040005565 PAGE: 17-22 claimed sequence, 22: PN: US20040014051 PAGE: 23 claimed sequence, 23: PN: US20040014699 PAGE: 20 claimed sequence, 24: PN: US20040006029 PAGE: 23 claimed sequence, 24: PN: WO03106645 PAGE: 73 claimed sequence
• Brand: TRC

Description

Applications N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine is a commonly used reactant in the preparation of nucleosidic phosphoramidite derivatives.
References Sanghvi, Y.S., et. al.: Org. Process Res. Dev., 4, 175 (2000); Xie, C., et. al.: Org. Process Res. Dev., 9, 730 (2005); Cheruvallath, Z.S., et. al.: Org. Process Res. Dev., 10, 251 (2006)

Chemical properties

• Molecular weight: 731.79
• Formula: C₄₁H₄₁N₅O₈
• Color/Form: Neat
• InChI: InChI=1S/C41H41N5O8/c1-49-22-23-52-36-35(47)33(54-40(36)46-26-44-34-37(42-25-43-38(34)46)45-39(48)27-10-6-4-7-11-27)24-53-41(28-12-8-5-9-13-28,29-14-18-31(50-2)19-15-29)30-16-20-32(51-3)21-17-30/h4-21,25-26,33,35-36,40,47H,22-24H2,1-3H3,(H,42,43,45,48)/t33-,35-,36-,40-/m1/s1
• InChI key: InChIKey=KEVMXGNDTKPSMC-GFNWNWSYSA-N
• SMILES: COCCOC1C(O)[C@@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21