(R)-Betaxolol Hydrochloride

CAS: 91878-54-5

Ref. TR-B327990

Product Information

• Name: (R)-Betaxolol Hydrochloride
• Synonyms: 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride (1:1), (2R)- (ACI), (2R)-1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol hydrochloride (1:1) (ACI), 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride, (R)- (9CI), (R)-1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)propan-2-ol hydrochloride
• Brand: TRC
• Description: Applications (R)-Betaxolol is the R-isomer of Betaxolol (B328000), a cardioselective β1-adrenergic blocker (1,2,3). It is also an antihypertensive and antiglaucoma agent (4).References (1) Bickel, M., et al.: J. Pharm. Pharmacol., 32, 669 (1980)(2) Cadigan, P.J., et al.: Br. J. Clin. Pharmacol., 9, 569 (1980) (3) Pathe, M., et al.: Therapie, 37, 75 (1982)(4) Panchal, V. S., et al.: J. Pharm. Sci. Pharmacol. 2, 21 (2015)

Chemical properties

• Molecular weight: 343.89
• Formula: C₁₈H₂₉NO₃·ClH
• Color/Form: Neat
• InChI: InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H/t17-;/m1./s1
• InChI key: InChIKey=CHDPSNLJFOQTRK-UNTBIKODSA-N
• SMILES: CC(C)NC[C@@H](O)COc1ccc(CCOCC2CC2)cc1.Cl