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Betulin

CAS:

Ref. TR-B330240

1g
179.00€
5g
285.00€
25g
651.00€
Betulin
TRC

    Product Information

    Name:Betulin
    Controlled Product
    Synonyms:
    • Lup-20(29)-ene-3β,28-diol
    • Lup-20(30)-ene-3β,28-diol
    • 3aH-Cyclopenta[a]chrysene
    • lup-20(29)-ene-3,28-diol deriv.
    • 3,28-Dihydroxy-lupeol
    • 3β,28-Dihydroxylup-20(29)-ene
    • Betuline
    • Betulinic alcohol
    • Betulinol
    • Betulol
    • See more synonyms
    Brand:TRC
    Description:Stability HygroscopicApplications Betulin is a derivative of Betulinic Acid (B330250), used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activityReferences Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010);
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:442.72
    Formula:C30H50O2
    Color/Form:White Powder
    InChI:InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1
    InChI key:InChIKey=FVWJYYTZTCVBKE-PYODEANISA-N
    SMILES:C=C(C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)[C@@H]12

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